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Ewing sarcoma is a malignant bone tumor, and its early detection is critically important. It is one of the most common types of sarcoma in adolescents and young adults.
The disease most frequently affects bones, particularly those of the lower and upper extremities and the pelvis. In some cases, soft tissues may also be involved. Early diagnosis is essential, as it significantly impacts treatment outcomes.
There are two main stages of the disease:
Localized disease – when the tumor is confined to the bone or adjacent tissues. In such cases, treatment success rates reach approximately 70–75%.
Metastatic disease – when the cancer has spread to distant organs, including the lungs, other bones, or bone marrow. In these cases, the likelihood of cure decreases significantly, to 15–30% (sometimes lower).
Common Symptoms
Pain and swelling at the tumor site
Palpable mass with localized warmth
Fever of unknown origin or pathological fractures
Diagnosis
Diagnostic evaluation includes X-ray, CT, MRI, and PET/CT imaging. The definitive diagnosis is established based on histopathological examination of tumor tissue.
Treatment
In Armenia, treatment for Ewing sarcoma is provided at the “Yolyan” Hematology and Oncology Center, which hosts the country’s only pediatric oncology unit.
The center is a member of the Euro Ewing Consortium and follows international treatment protocols (both American and European guidelines). Treatment outcomes in Armenia are consistent with international benchmarks.
Comprehensive treatment—including chemotherapy, radiotherapy, and, when indicated, surgical intervention—is fully available in Armenia, owing to the high level of expertise of local specialists. The financial burden is fully covered by the state and the City of Smile Charitable Foundation.
What is Ewing Sarcoma?
Ewing sarcoma is a malignant bone tumor, and its early detection is critically important. It is one of the most common types of sarcoma in adolescents and young adults. The disease most frequently affects bones, particularly those of the lower and upper extremities and the pelvis. In some cases, soft tissues may also be involved. …
Unexplained Skin Rash and Severe Hyperlipidemia: Therapeutic Plasmapheresis as an Effective Solution
Clinical Presentation and Examination A 38-year-old female patient presented with a widespread, progressive skin rash covering a large surface area of the body (xanthelasma-like lesions), which had persisted for a long period and demonstrated progression over time. The rash was not associated with pain. Laboratory tests prescribed by a dermatologist revealed extremely elevated lipid levels: …
Congratulations on March 8 – International Women’s Day․ Hayk Grigoryan
Dear women and girls, I warmly congratulate you on March 8 – International Women’s Day. This occasion is yet another opportunity to recognize and appreciate the vital role and contributions of women across all areas of public life, particularly in healthcare. At the “Yeolyan” Hematology and Oncology Center, we witness every day your professionalism, dedication, …
Bone Marrow Transplantation: Opportunities and Challenges in Armenia
Allogeneic bone marrow transplantation may be associated with various complications that patients need to overcome during treatment. It is essential to diagnose these complications promptly, manage them effectively, and prevent them whenever possible. Karen Meliksetyan, Head of the Bone Marrow Transplantation Department at the “Yeolyan” Hematology and Oncology Center, was a guest on the Public …
Modern Approaches to the Treatment of Myelodysplastic Syndromes: Scientific Meeting at the “Yeolyan” Center
Recently, the “Yeolyan” Hematology and Oncology Center hosted Dr. Ekaterina Balayan, a hematologist from the Carl Gustav Carus University Hospital in Dresden, Germany, who is the author of numerous scientific papers and publications, as well as a participant in international research projects. Dr. Balayan delivered a presentation titled “Modern Approaches to the Diagnosis and Treatment …
Collaboration for Life: Expanding the Blood Donation Promotion Program
The blood donation initiative is evolving into a united movement. Medical institutions joining the campaign are creating a broad platform for cooperation, contributing to the sustainable development of a culture of voluntary, non-remunerated blood donation in Armenia. In February, the joint program of the “Yeolyan” Hematology and Oncology Center and the Ministry of Health of …
February 28 marks International Rare Disease Day
This day serves as an important reminder of the need to raise awareness about diseases that, while rare, leave patients particularly vulnerable. Diagnosis is often delayed, and the path to appropriate treatment can be long and complex. In this context, hematologist Yervand Hakobyan from the “Yeolyan” Hematology and Oncology Center was featured as a guest …
To date, 25 allogeneic transplants have been performed in Armenia
Allogeneic transplantation is one of the most complex medical procedures, during which a patient’s immune system and blood-forming cells are replaced with compatible donor cells. In cases of severe malignant blood disorders, it is often the only effective treatment option, offering the possibility of complete recovery. Implementing such a program requires a high level of …
21,600 Capsules of “Kelfer” Donated to the Yeolyan Center by the Embassy of India
Healthcare cooperation between Armenia and India continues. For many years, the Embassy of India has been providing the Yeolyan Hematology and Oncology Center with the medication Kelfer. The Ambassador Extraordinary and Plenipotentiary of India, Nilakshi Saha Sinha, visited the Yeolyan Hematology and Oncology Center of the Ministry of Health of the Republic of Armenia and …