Find a doctor 
Contact us 
Colorectal cancer is a common malignant disease influenced by both environmental and hereditary factors. Among all malignant diseases, it ranks third in frequency among men and second among women.
The main risk factors include
- age,
- chronic inflammatory bowel diseases (particularly ulcerative colitis and Crohn’s disease),
- a history of abdominal or pelvic radiotherapy, and cystic fibrosis.
Other contributing risk factors are the consumption of red and processed meat, alcohol abuse, smoking, obesity, and diabetes mellitus.
Colorectal cancer can occur in sporadic or familial forms.
Sporadic cases: This form develops without hereditary predisposition and accounts for the majority of cases (over 70%). It is mainly associated with external factors such as poor diet, infections, and harmful habits (smoking, alcohol consumption).
Familial cases (adenomatous polyposis and Lynch syndrome): About 10–15% of colorectal cancers are linked to hereditary mutations or genetic disorders. In such cases, several family members may have colorectal cancer or multiple polyps, and the disease tends to develop at a younger age, around 40–45 years.
Diagnosis of colorectal cancer is performed by colonoscopy.
Treatment choice depends on the stage of disease and the presence of specific mutations. Management may include surgical intervention, as well as medical approaches such as chemotherapy, immunotherapy, targeted therapy, and radiotherapy.
