Find a doctor 
Contact us 
This type of coagulopathy develops when certain toxic agents or medications interfere with blood clotting. The most common cause is warfarin, which blocks the normal action of vitamin K. Rodenticides act through the same mechanism. In addition, venom from certain snakes can directly destroy coagulation factors.
Clinical manifestations: Bruising, nasal and gingival bleeding, gastrointestinal or urinary tract hemorrhages. In severe cases, life-threatening intracranial hemorrhages may occur.
Diagnosis: Based on patient history and laboratory findings. Typically, both PT and aPTT are prolonged.
Treatment: The goal is to neutralize the effect of the toxin and restore normal hemostasis.
